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The reasons why OHL is a rare symptom in HIV-1-infected children, compared with HIV-1-infected adults, are discussed. For instance, in plant cells, isoforms have been identified for the MPN-domain subunits CSN5 (CSN5A and CSN5B) and CSN6 (CSN6A and CSN6B) which form four distinct CSN variants. Cognitive function after several years of antiretroviral therapy with stable central nervous system penetration score.
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